SLU  |  SLU SOM  |  Biochemistry | 

Publications

  • Gonzalo S. DNA damage and lamins. Adv Exp Med Biol 2014; 773:377-99. PMID:24563357
  • Das A*, Grotsky DA*, Neumann MA, Gonzalez-Suarez I, Redwood AB, Stewart CL, Dusso A, Gonzalo S. Lamin A Δexon9 mutation leads to telomere and chromatin defects but not genomic instability. Nucleus 2013 Sept 1; 4(5):410-9. PMID:24153156
  • Croke M*, Neumann MA*, Grotsky DA, Kreienkamp R, Yaddanapudi SC, Gonzalo S. Differences in 53BP1 and BRCA1 regulation between cycling and non-cycling cells. Cell Cycle 2013 Dec 1; 12(23):3629-39. PMID:24091731
  • Gonzalo S. Novel roles of 1α,25(OH)2D3 on DNA repair provide new strategies for breast cancer treatment. J Steroid Biochem Mol Biol 2014 Oct; 144PA:59-64. PMID:24080249
  • Vindigni A, Gonzalo S. The two faces of DNA repair: disease and therapy. MO Med 2013 Jul-Aug; 110(4):314-9. PMID: 24003649
  • Grotsky DA, Gonzalez-Suarez I*, Novell A*, Neumann MA, Yaddanapudi SC, Croke M, Martinez-Alonso M, Redwood AB, Ortega-Martinez S, Feng Z, Lerma E, Ramon y Cajal T, Zhang J, Matias-Guiu X, Dusso A and Gonzalo S. BRCA1 loss activates cathepsin L-mediated degradation of 53BP1 in breast cancer cells. J Cell Biol 2013 Jan 21; 200(2):187-202. PMID:23337117
  • Redwood AB, Perkins SM, Vanderwaal RP, Feng Z, Biehl KJ, Gonzalez-Suarez I, Morgado-Palacin L, Shi W, Sage J, Roti-Roti JL, Stewart CL, Zhang J and Gonzalo S. A dual role for A-type lamins in DNA double-strand breaks repair. Cell Cycle 2011 Nov 1; 10(21):3652-7. Extra Views
  • Gonzalez-Suarez I, Redwood AB, Grotsky DA, Neumann MA, Cheng E, Stewart CL, Dusso A, and Gonzalo S. A new pathway that regulates 53BP1 stability implicates Cathepsin L and Vitamin D in DNA repair. EMBO J 2011 Jul 12; 30(16):3383-96.
  • Chen H, Ma Z, Vanderwaal RP, Feng Z, Gonzalez-Suarez I, Wang S, Zhang J, Roti Roti JL, Gonzalo S, Zhang J. The mTOR inhibitor Rapamycin suppresses DNA double-strand break repair. Radiat Res 2011 Feb; 175(2):214-24.
  • Gonzalo S. Epigenetics alterations in aging. J Appl Physiol 2010 Aug; 109(2):586-97. Review
  • Shi W, Feng Z, Zhang J, Gonzalez-Suarez I, Vanderwaal RP, Wu X, Powell SN, Roti Roti JL, Gonzalo S, Zhang J. The Role of RPA2 phosphorylation in homologous recombination in response to replication arrest. Carcinogenesis 2010 Feb 3; 31(6):994-1002.
  • Gonzalez-Suarez I and Gonzalo S. Nurturing the genome: A-type lamins preserve genomic stability. Nucleus 2010 Mar-Apr; 1(2):129-35. Extra Views
  • Gonzalez-Suarez I, Redwood AB, Gonzalo S. Loss of A-type lamins and genomic instability. Cell Cycle 2009 Dec; 8(23):3860-5. Extra Views
  • Gonzalez-Suarez I*, Redwood AB*, Perkins SM, Vermolen B, Lichtensztejin D, Grotsky DA, Morgado-Palacin L, Gapud E, Sleckman BP, Sullivan T, Sage J, Stewart CL, Mai S and Gonzalo S. Novel roles for A-type lamins on telomere biology and the DNA damage response pathway. EMBO J. 2009 Aug 19; 28(16):2414-27.
  • Zeng S, Xiang T, Pandita TK, Gonzalez-Suarez I, Gonzalo S, Harris CC, Yang Q. Telomere recombination requires the MUS81 endonuclease. Nat Cell Biol 2009 May; 11(5):616-23.
  • Gonzalez-Suarez I and Gonzalo S. Crosstalk between chromatin structure, nuclear compartmentalization, and telomere biology. Cytogenet Genome Res 2008; 122:202-210. Review
  • Jones B, Su H, Bhat A, Lei H, Bajko J, Hevi S, Baltus GA, Kadam S, Zhai H, Valdez R, Gonzalo S, Zhang Y, Li E, Chen T. The histone H3K79 methyltransferase Dot1L is essential for mammalian development and heterochromatin structure. PLoS Genet 2008 Sept 12; 4(9):e1000190.
  • Benetti R, Gonzalo S, Jaco I, Muñoz P, Gonzalez S, Schoeftner S, Murchison E, Andl T, Chen T, Klatt P, Li E, Serrano M, Millar S, Hannon G, Blasco MA. A mammalian micro RNA cluster controls DNA methylation and telomere recombination via Rb12-dependent regulation of DNA methyltransferases. Nat Struct Mol Biol 2008 Sep; 15(9):998.
  • Benetti R*, Gonzalo S*, Jaco I*, Schotta G, Klatt P, Jenuwein T, Blasco MA. Suv4-20h deficiency results in telomere elongation and derepression of telomere recombination. J Cell Biol 2007 Sep; 178(6):925-36.
  • Gonzalo S, Jaco I, Fraga MF, Chen T, Li E, Esteller M, Blasco MA. DNA methyltransferases control telomere length and telomere recombination in mammalian cells. Nat Cell Biol 2006 Apr; 8(4):416-24.
  • Gonzalo S and Blasco MA. Role of Rb family in the epigenetic definition of chromatin. Cell Cycle 2005 Jun; 4(6):752-5. Review
  • Gonzalo S*, García-Cao M*, Fraga MF, Schotta G, Peters AHFM, Cotter S, Eguía R, Dean DC, Esteller M, Jenuwein T, Blasco MA. Role of Rb family in stabilizing histone methylation at constitutive heterochromatin. Nat Cell Biol 2005 Apr; 7(4):420-8.
*Contributed equally to this work.
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