Molecular Mechanisms of thrombosis and Hemostasis

OUR GOAL

Targeted Diagnostics and Therapeutics

OUR APPROACH

It is hard to come up with game-changing new drugs without a more in-depth knowledge of the fundamental mechanisms of disease
Technology Platform

In our laboratory, we strive to understand the pathophysiological mechanisms that lead to thrombosis, autoimmunity and inflammation. To achieve our goals, we apply a unique combination of structural biology, single molecule spectroscopy, enzymology and protein engineering

  • X-ray crystallography, SAXS, Electron Microscopy

  • sm-PIE-FRET, smTIRF-FRET, FCS

  • kinetic assays, protein-protein interactions

  • Molecular Cloning, Mutagenesis, Incorporation of Non-Natural Amino Acids

OUR TEAM

Nicola Pozzi, Ph.D.

Mathivanan Chinnaraj, Ph.D.

William Planer, MS, MSF, MBA

CONTACT US

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