Sergey Korolev, Ph.D., Associate Professor of Biochemistry, recently received two research grants.
Sergey received a new grant from the NINDS entitled “Structural studies of PARK14.” The research will focus on solving the structure of the PARK14 enzyme, which is strongly associated with a variety of neurological diseases, including Parkinson’s disease. Understanding the structure of the enzyme will provide important information about its function and activity, and could result in new therapeutic treatments for human disease.
Sergey also received a Siteman Investment Program Grant for his project entitled “Mechanism and inhibition of PALB2 and BRCA2 proteins.” This research will focus on mutations in two tumor suppressor protein genes that can lead to cancer and resistance to cancer treatment. Inhibitors of these proteins will be investigated in order to improve the effectiveness of current cancer treatments or to find new treatments for the disease.