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Maureen Donlin, Ph.D.
Research Professor

Studies on the cell wall integrity signaling pathway in the human fungal pathogen Cryptococcus neoformans

Office: DRC 611
Voice: (314) 977-8858

Research Interests

The human fungal pathogen, Cryptococcus neoformans, is the focus of research in our laboratory. One arm of our research is to understand how C. neoformans regulates and remodels its cell wall in response to stress and antifungal therapies. A second arm of our research is to identify novel small molecules that can inhibit growth of the fungus and potentially be developed into new anti-fungal therapies.

Recent Publications

Troponoids Can Inhibit Growth of the Human Fungal Pathogen Cryptococcus neoformans
Donlin MJ, Zunica A, Lipnicky A, Garimallaprabhakaran AK, Berkowitz AJ, Grigoryan A, Meyers MJ, Tavis JE and Murelli RP

Hepatitis B virus genetic diversity has minimal impact on sensitivity of the viral ribonuclease H to inhibitors
Lu G, Villa JA, Donlin MJ, Edwards TC, Cheng X, Heier RF, Meyers MJ and Tavis JE

A Functional Interplay between Human Immunodeficiency Virus Type 1 Protease Residues 77 and 93 Involved in Differential Regulation of Precursor Autoprocessing and Mature Protease Activity
Counts CJ, Ho PS, Donlin MJ, Tavis JE and Chen C

Checkpoint blockade immunotherapy relies on T-bet but not Eomes to induce effector function in tumor-infiltrating CD8+ T cells
Berrien-Elliott MM, Yuan J, Swier LE, Jackson SR, Chen CL, Donlin MJ and Teague RM

Cross talk between the cell wall integrity and cyclic AMP/protein kinase A pathways in Cryptococcus neoformans
Donlin MJ, Upadhya R, Gerik KJ, Lam W, VanArendonk LG, Specht CA, Sharma NK and Lodge JK

Department of Biochemistry and Molecular Biology
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