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Education
Ph.D., 1972, National Taiwan University
Research Interests
The areas of research in this laboratory are: 1) autocrine transformation by the v-sis/c-sis oncogene and novel trans-Golgi network (TGN) signal transduction, and 2) role of the transforming growth factor ß (TGF-ß) type V receptor (TR-V) in the biological functions of TGF-ß.
Recent Publications
  • 7-Dehydrocholesterol (7-DHC), but not cholesterol, causes suppression of canonical TGF-beta signaling and is likely involved in the development of atherosclerotic cardiovascular disease (ASCVD).
    Huang SS, Liu IH, Chen CL, Chang JM, Johnson FE, Huang JS. J Cell Biochem. (2016) Nov 16 [Epub ahead of print].
  • DMSO enhances TGF-beta activity by recruiting the Type II TGF-beta receptor from intracellular vesicles to the plasma membrane.
    Huang SS, Chen CL, Huang FW, Hou WH, Huang JS. J Cell Biochem. (2016) 117(7):1568-1579.
  • Ethanol enhances TGF-beta activity by recruiting TGF-beta receptors From intracellular vesicles/lipid rafts/caveolae to non-lipid raft microdomains.
    Huang SS, Chen CL, Huang FW, Johnson FE, Huang JS. J Cell Biochem. (2016) 117(4):860-871.