“kisselev-r.jpg”

Oleg Kisselev, Ph.D.
Associate Professor

Studies on the mechanism of transmembrane signal transduction mediated by heterotrimeric G-proteins, which are responsible for the transmission of information about extracellular messangers.

Office: Schwitalla Hall 099
Voice: (314) 977-6301

Research Interests

We are interested in the universal mechanism of transmembrane signal transduction mediated by heterotrimeric G-proteins, which are responsible for the transmission of information about extracellular messengers such as hormones, neurotransmitters and sensory stimuli, including visual signals.

Recent Publications

Signaling states of rhodopsin in rod disk membranes lacking transducin βγ-complex
Lomonosova E, Kolesnikov AV, Kefalov VJ and Kisselev OG

G-protein betagamma-complex is crucial for efficient signal amplification in vision
Kolesnikov AV, Rikimaru L, Hennig AK, Lukasiewicz PD, Fliesler SJ, Govardovskii VI, Kefalov VJ and Kisselev OG

Electron paramagnetic resonance studies of functionally active, nitroxide spin-labeled peptide analogues of the C-terminus of a G-protein alpha subunit
Van Eps N, Anderson LL, Kisselev OG, Baranski TJ, Hubbell WL and Marshall GR

Using ligand-based virtual screening to allosterically stabilize the activated state of a GPCR
Taylor CM, Rockweiler NB, Liu C, Rikimaru L, Tunemalm AK, Kisselev OG and Marshall GR

Modulating G-protein coupled receptor/G-protein signal transduction by small molecules suggested by virtual screening
Taylor CM, Barda Y, Kisselev OG and Marshall GR

Department of Biochemistry and Molecular Biology
drc_mobile