James Shoemaker, M.D.
Associate Professor

Screening children for inborn errors of metabolism using gas chromatography-mass spectrometry and evaluation of special nutritional needs in children with Down's syndrome.

Office: DRC 431
Voice: (314) 977-9230

Research Interests

Our clinical activities include screening for inborn errors of metabolism in children by quantifying chemicals in body fluids by gas chromatography-mass spectrometry. We developed a new method of sample preparation which allows carbohydrates and amino and organic acids to be detected in the same sample. Our current research is concerned with the evaluation of special nutritional needs in children with Down syndrome and the diagnosis of vitamin deficiency by quantitation of urinary metabolites after an oral dose of amino acids and other food constituents.

Recent Publications

Regional cerebral cortical thickness correlates with autonomic outflow
Wood KN, Badrov MB, Speechley MR and Shoemaker JK

Cardiac Baroreflex Variability and Resetting during Sustained Mild Effort
Zamir M, Badrov MB, Olver TD and Shoemaker JK

Combined Dual-Task Gait Training and Aerobic Exercise to Improve Cognition, Mobility, and Vascular Health in Community-Dwelling Older Adults at Risk for Future Cognitive Decline1
Gregory MA, Boa Sorte Silva NC, Gill DP, McGowan CL, Liu-Ambrose T, Shoemaker JK, Hachinski V, Holmes J and Petrella RJ

High cardiorespiratory fitness in early to late middle age preserves the cortical circuitry associated with brain-heart integration during volitional exercise
Wood KN, Luchyshyn TA and Shoemaker JK

Effective Utilization of Computerized Curricular Assistive Tools in Improving NCLEX-RN Pass Rates for a Baccalaureate Nursing Program
Shoemaker JR, Chavez RA, Keane P, Butz S and Yowler SK

Department of Biochemistry and Molecular Biology