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We are still working on this beta version of the web site. Tools and database extensions will be added and opened gradually until the end of August, the date of the first complete version. You can find more about the schedule in "what's next ?"
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Serine Proteases

Tour

 

 

Introduction - Overview

Tutorials

Sequence Index

What's new

 

 

5 clans- 30 families - 700 sequences

What's next

Sequence Analyzer

Bugs & Stats

 

 

Make sequence sets - Align sequences - Analyze amino acid occurence

Evolution

 

 

Display amino acid occurence and filter specific positions through evolutionary trees

Mutations

 

 

Mutation catalog - Analyze position entropy - Correlate mutation effect and function

Structure Index

 

 

Select structures from sorted lists- Display imported PDB files in Chime or Rasmol

Structure Analyzer

 

 

Analyze structural features - Compare structures - Make scripts and display in Chime or Rasmol

Ligand Catalog & Analyzer

 

 

Catalogs of natural and synthetic substrates and inhibitors for selected proteases

Function

 

 

Track correlation of functions with sequences, structures or trees

Help

 

 

Help - References

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Go to the Washington University in St Louis
Go to the School of MedicineGo to the Department of Biochemistry and Molecular Biophysics

Thierry Rose, PhD and Enrico Di Cera, MD
Department of Biochemistry and Molecular Biophysics
Washington University School of Medicine
Saint Louis, MO, U.S.A.

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