menu also at the end of this page home Overview links search toolbox.html browser setup help contact us about Help and references Correlation with function Tour and Tutorials Evolutionary trees Substrate and inhibitor catalogs Mutations Structure analyzer Sequence analyzer Structure index Family and sequence index horiz_blue.gif
We are still working on this page. Catalogs and tools will be added and opened gradually until the end of August, the date of the first complete version of this web site. You can find more about the schedule in "what's next ?"
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Thrombin
tPA
Trypsin
Chymotrypsin
Position
Tolerance
Substitution-Function
Addition/Deletion-Function
Click the purple button in the menu above or the purple bullet in the descriptive menu below. A Red bullet means the corresponding page is not yet released. If you click on it you will find an estimate of the release date and its current state of development.
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Catalog Index

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release Thrombin : list, effects, references
release Tissue Plasminogen Activator : list, effects, references
release Trypsin : list, effects, references
release Chymotrypsin : list, effects, references
release Factor X : list, effects, references
release horiz_blue.gifMutation Catalog by position (menu: position)
Input: reference, position
Output: mutations, references
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Mutation analyzer

release horiz_blue.gif Position tolerance analyzer (menu:tolerance)
Input: reference, position, set of accession numbers
Output: tolerance to substitution, reference from indexed catalogs
release Correlation between functions and mutation effects (menu:substitution-function)
Input: reference, position, substitution, quantitative function
Output: correlation amino-acid properties/function
release Correlation between functions and mutation effects (menu:addition/deletion-function)
Input: reference, position, insertion or deletion quantitative function
Output: correlation added or lost amino-acid properties/function
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Go to the Washington University in St Louis
Go to the School of MedicineGo to the Department of Biochemistry and Molecular Biophysics

Thierry Rose, PhD and Enrico Di Cera, MD
Department of Biochemistry and Molecular Biophysics
Washington University School of Medicine
Saint Louis, MO, U.S.A.

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