menu also at the end of this page home Overview links search toolbox.html browser setup help contact us about Help and references Correlation with function Tour and Tutorials Evolutionary trees Substrate and inhibitor catalogs Mutations Structure analyzer Sequence analyzer Structure index Family and sequence index horiz_blue.gif
We are still working on this beta version. Tools, links and database extension will be added and opened gradually until the end of August, the date of the first release. You can find more about the schedule in "what's next ?"
horiz_blue.gif
Go to page bottom
Protease?
Classification?
Clan?
Family?
Sub-family?
Table
All sequences
Make sets
Search
 

 

To find sequences, click the link to the corresponding clan or family in the table below or click all serine proteases to access the entire list of serine proteases (500Kb-document). If you look for sequences to make sets go to sequence analyzer (make sets). You can browse your sequence from search. All these facilities allow you to get direct links to the sequence through the corresponding database

horiz_blue.gif
Go to page bottom  Overview of the Classification of Serine Proteases
See legends
Clan

Family

Seq
Pro
Enz
Str
3D
H-S-D-F-O-C

Representative enzyme

SA S1
339
 
40
 
37
H S D F O C Chymotrypsin
  S2
24
 
5
 
6
  Alpha-Lytic endopeptidase
  S2 A
11
 
4
 
5
H S D F O C Alpha-Lytic endopeptidase
  S2 B
5
 
1
 
1
H S D F O C Glutamyl endopeptidase (V8)
  S2 C
8
 
0
 
0
H S D F O C Protease Do (htrA) (Escherichia)
  S3
15
 
1
 
1
H S D F O C Togavirin
  S4
 
 
 
 
 
  S4 included in S2
  S5
1
 
1
 
0
H S D F O C Lysyl endopeptidase
  S6
8
 
1
 
0
H S D F O C IgA-specific serine endopeptidase
  S7
1
 
1
 
0
H S D F O C Flavivirin
  S29
1
 
1
 
1
H S D F O C Hepatitis C virus NS3 endopeptidase
  S30
1
 
0
 
0
H S D F O C Tobacco etch virus 35 Kd endopeptidase
  S31
4
 
0
 
0
H S D F O C Cattle diarrhea virus p80 endopeptidase
  S32
2
 
0
 
0
H S D F O C Equine arteritis virus putative endopeptidase
  S35
3
 
0
 
0
H S D F O C Apple stem grooving virus serine endopep.
SB S8
95
 
13
 
12
H S D F O C Subtilases
  S8A
?
 
8
 
12
H S D F O C Subtilisin
  S8B
?
 
4
 
0
H S D F O C Kexin
  S8C

?

 
1
 
0
H S D F O C Tripeptidyl-peptidase II
SC S9
26
 
 
 
 
H S D F O C Prolyl oligopeptidase
  S9A
10
 
2
 
0
H S D F O C Prolyl oligopeptidase
  S9B
10
 
1
 
0
H S D F O C Dipeptidyl-peptidase IV
  S9C
6
 
1
 
0
H S D F O C Acylaminoacyl-peptidase
  S10
33
 
5
 
4
H S D F O C Carboxypeptidase C
  S15
3
 
1
 
0
H S D F O C Lactococcus X-Pro dipeptidyl-peptidase
  S28
1
 
2
 
0
H S D F O C Lysosomal Pro-X carboxypeptidase
SE S11
13
 
1
 
1
H S D F O C D-Ala-D-Ala peptidase family 1
  S12
2
 
2
 
3
H S D F O C D-Ala-D-Ala peptidase family 2
  S13
4
 
1
 
0
H S D F O C D-Ala-D-Ala peptidase family 3
SG S14
30
 
1
 
1
H S D F O C ClpP endopeptidase
  S16
30
 
1
 
0
H S D F O C Endopeptidase La (Lon)
  S20
 
 
 
 
 
  S20 included in S2
SF S24
15
 
1
 
1
H S D F O C LexA repressor
  S25
 
 
 
 
 
  S25 is moved to threonine protease class
  S26
20
 
1
 
1
H S D F O C Bacterial leader peptidase I
  S27
5
 
 
 
 
H S D F O C Eukaryote signal peptidase
- S18
4
 
1
 
0
H S D F O C Omptin
- S19
1
 
0
 
0
H S D F O C Coccidiodes endopeptidase
- S21
16
 
1
 
3
H S D F O C Assemblin (Herpesviruses protease)
horiz_blue.gif
Go to page bottom  Legends:
    Clan & family = link to the corresponding sequences
Sequence = number of sequences - link to the most representative.
Proteases = number of different proteases, i.e. trypsins of different species are counted as 1.
Enzyme = number of enzymes with distinct E.C. entries.
Structures = total number of structures including a serine protease domain - link to the most representative.
3D = number of structures including distinct serine protease domains
HSSP - sequence alignment of the family from structural superpositions
ProSite - Patterns of the current family
ProDom - Homologous domains of the family
SCOP - structural classification of proteins - fold of the family
CATH - Structure classification of the family
Representative enzyme = link to corresponding sequence of family representative protease.
horiz_blue.gif
Go to page bottom

[HomePage] [Sequence Index] [Sequence Alignment] [Sequence Analyser] [Evolution] [Mutation] [Help]
[Structure Index] [Structure Viewer] [Substrates and Inhibitors] [Functions][About] [Contact_us] [Protic]

horiz_blue.gif
Go to the Washington University in St Louis
Go to the School of MedicineGo to the Department of Biochemistry and Molecular Biophysics

Thierry Rose, PhD and Enrico Di Cera, MD
Department of Biochemistry and Molecular Biophysics
Washington University School of Medicine
St. Louis, MO, U.S.A.

horiz_blue.gif
 

This web page has been updated the
© Copyright 1999 2000 - Netellise - All rights reserved.