Enrico Di Cera, M.D. » Investigators

Cardiovascular Research Interests:

Primary area of research:

• Thrombin

Related areas of research:

• Clotting factors

Summary of cardiovascular research:

My lab has been working on thrombin since 1990 and defined the functional and structural aspects of its interaction with Na+ and key physiological substrates. We have engineered and characterized all of the critical reagents that are essential to the performance of this work. The environment in my lab offers a unique combination of expertise in enzyme kinetics, molecular biology, thermodynamics and X-ray structural biology that is ideal for the training of students and postdoctoral fellows interested in the molecular basis of protease function and cardiovascular disease.