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2nd Doisy Conference on Coagulation
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The 2nd Doisy Conference on Coagulation (DCC2) will take place on Monday, May 4, 2026, at the Missouri Botanical Garden Bayer Event Center located at 4344 Shaw Blvd., St. Louis, MO.

The DCC2 is a one-day event for researchers and trainees in the biomedical sciences. The event will consist of talks grouped in several sessions as well as a reception and poster session.

Questions? Contact Samantha Deavila (Email)

Organizers: Enrico Di Cera, M.D., and Rodney Camire, Ph.D.

Sponsors:

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DCC2 Final Agenda:
Sunday, May 3:

All Day:

Out-of-town arrivals

Monday, May 4:

8:00 – 9:00 am:

Registration, Light breakfast, Introductions

Session 1: Structure-Function I
Chair: Enrico Di Cera, M.D.

9:00 – 9:30 am:

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Rodney Camire, Ph.D.
Professor
Department of Pediatrics
University of Pennsylvania Perelman School of Medicine

“APC anticoagulant function of FV: New mechanistic insights”

9:30 – 10:00 am:

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Wolfram Ruf, Ph.D.
Professor
Department of Immunology & Microbiology
The Scripps Research Institute

“How coagulation shapes the bone marrow niche”

10:00 – 10:30 am:

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Josepha Sedzro, Ph.D.
Research Fellow
Department of Biological Chemistry
University of Michigan Medical School

“Cryo-EM reveals how tissue factor pathway inhibitor interacts with the membrane-bound TF/FVIIa/FXa complex”

10:30 – 10:45 am:

Coffee Break

Session 2: Structure-Function II
Chair: Rodney Camire, Ph.D.

10:45 – 11:15 am:

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David Gailani, M.D.
Professor
Department of Pathology & Microbiology & Immunology and Department of Medicine, Division of Hematology Oncology
Vanderbilt University Medical Center

“Interactions between prekallikrein and factor XII”

11:15 – 11:45 am:

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Karin Leiderman, Ph.D.
Associate Professor
Departments of Mathematics, Biochemistry & Biophysics, and Computational Medicine
University of North Carolina-Chapel Hill

“Mathematical modeling reveals mechanisms that mask phenotype discrimination in FXI deficiency”

11:45 am – 12:15 pm:

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Bassem Mohammed, Ph.D.
Assistant Professor
Department of Biochemistry & Molecular Biology
Saint Louis University School of Medicine

“Exosite-mediated activation of factor IX by factor Xia”

12:15 – 12:40 pm:

Complimentary lunch 

12:40 – 1:00 pm:

Lunch and Learn with ThermoFisher:

Natalie Young, Ph.D.

Sr. Product Specialist, Live Science Electron Microscopy

“Advancements and future of cryo-EM”

1:00 – 1:45 pm:

Visit the MO Botanical Garden grounds

Session 3: Structure-Function III
Chair: David Gailani, M.D.

1:45 – 2:15 pm:

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Weikai Li, Ph.D.
Roy and Diana Vagelos Distinguished Professor
Department of Biochemistry & Molecular Biophysics
Washington University School of Medicine

“From venom to vessel: The ancient biochemistry of vitamin K-dependent gamma-carboxylation”

2:15 – 2:45 pm:

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James Morrissey, Ph.D.
Professor
Department of Biological Chemistry
University of Michigan Medical School

“Insights from cryo-EM reveal how the membrane surface regulates the initiator complex of the blood clotting cascade”

2:45 – 3:15 pm:

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Nicola Pozzi, Ph.D.
Associate Professor
Department of Biochemistry & Molecular Biology
Saint Louis University School of Medicine

“Structural insights into thrombotic autoimmunity: Antiphospholid antibodies in APS”

3:15 – 3:30 pm:

Coffee Break

Session 4: Clinical-Translational
Chair: Jorge Di Paola, M.D.

3:30 – 4:00 pm:

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Robert Campbell, Ph.D.
Associate Professor
Department of Emergency Medicine
Washington University School of Medicine

“Novel regulators of platelets function in inflammation and thrombosis”

4:00 – 4:30 pm:

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Alvin Schmaier, M.D.
Professor
Departments of Medicine and Pathology
Case Western Reserve University School of Medicine

“The pathogenesis and treatment of cerebral malaria”

4:30 – 5:00 pm:

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Josh Siner, M.D.
Instructor
Department of Medicine, Division of Hematology
Washington University School of Medicine

“Tumor necrosis factor-alpha drives hyperreactive platelet production through signaling on hematopoietic stem and progenitor cells”

6:00 – 11:00 pm:

DCC2 Reception and Poster Session (Angad Arts Hotel, 3550 Samuel Shepard Dr.)

Details

Date: May 4
Time: 8:00 am - 5:00 pm

Location

Missouri Botanical Garden – Bayer Event Center
4344 Shaw Blvd.
St. Louis, MO 63110 United States
Department of Biochemistry and Molecular Biology
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