“Measuring what really matters: affinity determination in complex samples and with challenging proteins”

Contact Yuna Ayala (Email) for Zoom meeting link.

Topics discussed:

• Introduction to Microfluidic Diffusional Sizing
• Case study 1: COVID-19: quantitative information the concentration and affinity of antibodies in polyclonal serum samples provides deeper understanding of the immune response to SARS-CoV-2
• Case study 2: Amyloid beta peptide: measuring binding to monomeric and fibrillar forms provides useful insights into the mechanism of action of therapeutic antibodies
• Case study 3: beyond protein-protein interactions: MDS with SMALPs, aptamers, and small molecules

Fluidic Analytics is a biotech company originating from the University of Cambridge, established in 2013, and headquartered in Cambridge, UK. Fluidic Analytics provides a unique technology, Microfluidic Diffusional Sizing (MDS), which enables the rapid characterization of proteins based on the physical properties that determine their function.