“Novel function and mechanism of PALB2 in DNA repair and cancer”
“Mechanisms driving NRF2 activation in cancer”
“The Lord of the Rings: The structural mechanism of a sliding clamp loader”
“High basal levels of gH2AX in human induced pluripotent stem cells are linked to replication-associated DNA damage and repair” Reference: Vallabhanenia H, et al., Stem Cells, 36(10):1501-1513, 2018 (PMID: 29873142)
“Hexameric helicase action in replication and recombination”
"Cryo-EM structure of the Rous sarcoma virus stable synaptic complex (SSC) trapped by an HIV-1 integrase (IN) strand transfer inhibitor"
“Development of a CRISPR/Cas9-based therapy for Hutchinson-Gilford progeria syndrome” References: Santiago-Fernandez O, et al., Nat Med, 25(3):423-426, 2019 (PMID: 30778239) Beyret E, et al., Nat Med, 25(3):419-422, 2019 (PMID: 30778240)
“Hijacking the interferon response in PDGFRb-driven connective tissue disease”
RESEARCH UPDATE: “Structure and dynamics of protein disulfide isomerase revealed by single molecule FRET”
The 7th annual Structural Dynamics of Biomolecules Symposium will take place on Friday, December 13, 2019 in the Allied Health Building Auditorium. This year, the 36th Robert E. Olson lecture will be given in conjunction with the symposium by…
“Age-dependent sepsis severity and chronic critical illness in animal models”
"Heat & tension: How actomyosin-mediated elasticity regulates brown adipose tissue activity"
“Circadian lipid synthesis in brown fat maintains murine body temperature during chronic cold” Reference: Adlanmerini M, et al., Proc Natl Acad Sci USA, 116(37):18691-18699, 2019 (PMID: 31451658)
Collaborative Project Proposal: "Role of MBOAT7 in NASH" with Brent Tetri, M.D., and Barbara Ulmasov, Ph.D., of the Department of IM-Gastroenterology
"Progranulin: At the interface of neurodegenerative and metabolic diseases"
