“Location, Location, Location: Compartmentalizing biochemical reactions in cancer cells with metabolomics”
"To abort, or not to abort, that is the question: Hamlet insights into transcription initiation" Reference: Dulin D, et al., Nat Commun 9(1):1478-1489, 2018 (PMID: 29662062). A light lunch will be served. If you plan to eat lunch, please…
"Hydrogel cell scaffolds as in vitro models for drug screening applications"
“Structural chromosome maintenance in bacteria: Mechanism and drug discovery”
"New mechanisms of vertebrate DNA repair"
“A mitosis-specific and R loop-driven ATR pathway promotes faithful chromosome segregation” Reference: Kabeche L. et al., Science, 359(6371):108-114, 2018 (PMID: 29170278).
“Squish and squeeze: Nuclear mechanics in physiology and disease”
“DUX4 causes facioscapulohumeral dystrophy by activating a developmental program in skeletal muscle”
"Structural insights into G protein coupled receptor actions" A reception will be held immediately following the lecture.
"Mechanisms of DNA repair during replication"
The retreat will take place at the Donald Danforth Plant Science Center on Friday, October 12, 2018. Download a schedule of events: BMB Retreat Schedule 2018
Research Update: PALB2 N-terminal DNA binding residues are essential for Homology Dependent Repair and for strand exchange activity with ssDNA and RNA
"An FGFR inhibitor and the case for biomarkers"
"The CFTR protein in cystic fibrosis: Importance of knowing when to hold and when to fold" References: Hutt DM, et al., J Biol Chem, 293(35):13682-13695, 2018 (PMID: 29986884). Hutt DM, et al., J Biol Chem, 293(35):13477-13495, 2018 (PMID: 300006345).
“Investigations of the diabetic vasculature using novel metabolomic technologies”
