Dr. Ford Receives Grants

Dr. Ford was awarded two grants from the NIH.

The first is a 1-year grant from the NIGMS entitled “Neutrophil-dependent mediators of sepsis.” This project will use untargeted lipidomics to identify new mediators and prognostic biomarkers of multi-organ failure during sepsis.

He will also receive a supplement to the NIGMS award entitled “Chlorinated lipids in sepsis.” This grant is an equipment supplement that will be used to purchase a high resolution mass spectrometer.

Dan Pike Receives Award

Congratulations to M.D./Ph.D. Student, Dan Pike,

who has been awarded an F30 Ruth L. Kirschstein Individual Predoctoral National Research Service Award for M.D./Ph.D. and Dual Degrees Fellowship from the NIH for his project entitled “Plasmalogen-derived chlorinated lipids: Mediators of acute lung injury during sepsis.”

The Kirschstein-NRSA award is given to promising predoctoral students in dual degree programs who plan on careers as physician-scientists in order to enhance their research and clinical training.

Congratulations to Elisa Palladino

Congratulations to Dr. Elisa Palladino,

who successfully defended her dissertation entitled, “2-Chlorofatty acids function as new lipid mediators in neutrophil extracellular trap formation and accelerate their own clearance by inducing PPAR-alpha activity” on Wednesday, April 18, 2018.

Sepsis and ARDS

The Ford lab published a paper linking sepsis to

lung injury and death in patients with elevated levels of chlorinated lipids. Their findings were published in the Journal of Clinical Investigation Insight.

The paper shows that the presence of chlorinated lipids in patient blood samples at the time of  hospital admission predicted whether ARDS, or acute repiratory distress syndrome, would develop as well as whether the lung injury would result in death within 30 days.

Read the full story in Newslink.

ASBMB Hill Day

Congratulations to Celine Hartman!

Celine was selected to participate in the 2017 ASBMB Hill Day on April 6. Each year, students and postdocs apply to the event and a select few are invited to travel to Washington, DC, to meet and directly interact with their congressional representatives to advocate for scientific research and research funding.

Participants learned about the federal budget process, and had the opportunity to discuss their federally-funded research with congress members.

You can read more about Celine’s experience on Capitol Hill in Newslink.

GSA Awards

Congratulations to Graduate Students Daniel Pike and Celine Hartman for their awards from the Graduate Student Association. Both Dan and Celine presented posters at the 23rd annual Graduate Research Symposium in March.

Dan received 2nd place for his poster, and Celine received 3rd place for her poster. Winners were chosen from over 116 paper and poster presentations.

You can read the full story in Newslink.

Dan Pike
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Celine Hartman

Sepsis Grant from NIGMS

The Ford lab received a new multi-PI, multi-center

grant from the NIGMS entitled “Chlorinated lipids in sepsis.” Jane McHowat, Ph.D., of the Department of Pathology at SLU, is a Co-PI on the grant. Other investigators on the proposal include Thomas Cho, Ph.D., of the Department of Biochemistry, and Ron Korthuis, Ph.D., of the Department of of Medical Pharmacology and Physiology at the University of Missouri-Columbia School of Medicine.

The research will focus on determining the role of chlorinated lipids in vascular collapse and multiorgan failure during sepsis. These lipids are produced when

 leukocytes are activated following development of sepsis and can lead to endothelial dysfunction, platelet activation, and organ damage. They hope to find one or more biomarkers that can be used to determine when sepsis might develop, allowing for quicker diagnosis and treatment.

Please see the full story in Newslink.