Publications

Tian Y, Lu W, Shi R, McGuffee R, Lee R, Ford DA and Wang B. Targeting phospholipid remodeling pathway improves insulin resistance in diabetic mouse models. (2023) FASEB J. 37, e23251 Pubmed FASEB J PMC Article

Rasi V, Phelps KR, Paulson KR, Eickhoff CS, Chinnaraj M, Pozzi N, Di Gioia M, Zanoni I, Shakya S, Carlson HL, Ford DA, Kolar GR and Hoft DF. Homodimeric Granzyme A opsonizes Mycobacterium tuberculosis and inhibits its intracellular growth in human monocytes via TLR4 and CD14. (2023) J Infect Dis. Pubmed J Infect Dis

Mukherjee S, Chakraborty M, Msengi EN, Haubner J, Zhang J, Jellinek MJ, Carlson HL, Pyles K, Ulmasov B, Lutkewitte AJ, Carpenter D, McCommis KS, Ford DA, Finck BN, Neuschwander-Tetri BA and Chakraborty A. Ube4A maintains metabolic homeostasis and facilitates insulin signaling in vivo. (2023) Mol Metab. 75, 101767 Pubmed Mol Metab PMC Article

Tian Y, Mehta K, Jellinek MJ, Sun H, Lu W, Shi R, Ingram K, Friedline RH, Kim JK, Kemper JK, Ford DA, Zhang K and Wang B. Hepatic Phospholipid Remodeling Modulates Insulin Sensitivity and Systemic Metabolism. (2023) Adv Sci (Weinh). 10, e2300416 Pubmed Adv Sci (Weinh) PMC Article

Tian Y, Jellinek MJ, Mehta K, Seok SM, Kuo SH, Lu W, Shi R, Lee R, Lau GW, Kemper JK, Zhang K, Ford DA and Wang B. Membrane phospholipid remodeling modulates nonalcoholic steatohepatitis progression by regulating mitochondrial homeostasis. (2023) Hepatology. Pubmed Hepatology PMC Article

Shakya S, Pyles KD, Albert CJ, Patel RP, McCommis KS and Ford DA. Myeloperoxidase-derived hypochlorous acid targets human airway epithelial plasmalogens liberating protein modifying electrophilic 2-chlorofatty aldehydes. (2023) Redox Biol. 59, 102557 Pubmed Redox Biol PMC Article

Shakya S, McGuffee RM and Ford DA. Characterization of N-Acetyl Cysteine Adducts with Exogenous and Neutrophil-Derived 2-Chlorofatty Aldehyde. (2023) Antioxidants (Basel). 12, Pubmed Antioxidants (Basel) PMC Article

Jolliffe DA, Holt H, Greenig M, Talaei M, Perdek N, Pfeffer P, Vivaldi G, Maltby S, Symons J, Barlow NL, Normandale A, Garcha R, Richter AG, Faustini SE, Orton C, Ford D, Lyons RA, Davies GA, Kee F, Griffiths CJ, Norrie J, Sheikh A, Shaheen SO, Relton C and Martineau AR. Effect of a test-and-treat approach to vitamin D supplementation on risk of all cause acute respiratory tract infection and covid-19: phase 3 randomised controlled trial (CORONAVIT). (2022) BMJ. 378, e071230 Pubmed BMJ PMC Article

Palladino END, Bernas T, Green CD, Weigel C, Singh SK, Senkal CE, Martello A, Kennelly JP, Bieberich E, Tontonoz P, Ford DA, Milstien S, Eden ER and Spiegel S. Sphingosine kinases regulate ER contacts with late endocytic organelles and cholesterol trafficking. (2022) Proc Natl Acad Sci U S A. 119, e2204396119 Pubmed Proc Natl Acad Sci U S A PMC Article

Shakya S, Herr RA, Carlson HL, Zoeller RA, Albert CJ and Ford DA. Endothelial Cell Protein Targeting by Myeloperoxidase-Derived 2-Chlorofatty Aldehyde. (2022) Antioxidants (Basel). 11, Pubmed Antioxidants (Basel) PMC Article

Mukherjee S, Chakraborty M, Ulmasov B, McCommis K, Zhang J, Carpenter D, Msengi EN, Haubner J, Guo C, Pike DP, Ghoshal S, Ford DA, Neuschwander-Tetri BA and Chakraborty A. Pleiotropic actions of IP6K1 mediate hepatic metabolic dysfunction to promote nonalcoholic fatty liver disease and steatohepatitis. (2021) Mol Metab. 54, 101364 Pubmed Mol Metab PMC Article

Amunugama K, Jellinek MJ, Kilroy MP, Albert CJ, Rasi V, Hoft DF, Shashaty MGS, Meyer NJ and Ford DA. Identification of novel neutrophil very long chain plasmalogen molecular species and their myeloperoxidase mediated oxidation products in human sepsis. (2021) Redox Biol. 48, 102208 Pubmed Redox Biol PMC Article

Alishlash AS, Sapkota M, Ahmad I, Maclin K, Ahmed NA, Molyvdas A, Doran S, Albert CJ, Aggarwal S, Ford DA, Ambalavanan N, Jilling T and Matalon S. Chlorine inhalation induces acute chest syndrome in humanized sickle cell mouse model and ameliorated by postexposure hemopexin. (2021) Redox Biol. 44, 102009 Pubmed Redox Biol PMC Article

Addis DR, Lambert JA, Ford DA, Jilling T and Matalon S. Halogen gas exposure: toxic effects on the parturient. (2021) Toxicol Mech Methods. 31, 272-287 Pubmed Toxicol Mech Methods PMC Article

Liu X, Hartman CL, Li L, Albert CJ, Si F, Gao A, Huang L, Zhao Y, Lin W, Hsueh EC, Shen L, Shao Q, Hoft DF, Ford DA and Peng G. Reprogramming lipid metabolism prevents effector T cell senescence and enhances tumor immunotherapy. (2021) Sci Transl Med. 13, Pubmed Sci Transl Med

Khojandi N, Kuehm LM, Piening A, Donlin MJ, Hsueh EC, Schwartz TL, Farrell K, Richart JM, Geerling E, Pinto AK, George SL, Albert CJ, Ford DA, Chen X, Kline J and Teague RM. Oxidized Lipoproteins Promote Resistance to Cancer Immunotherapy Independent of Patient Obesity. (2021) Cancer Immunol Res. 9, 214-226 Pubmed Cancer Immunol Res PMC Article

Masjoan Juncos JX, Shakil S, Bradley WE, Wei CC, Zafar I, Powell P, Mariappan N, Louch WE, Ford DA, Ahmad A, Dell'Italia LJ and Ahmad S. Chronic cardiac structural damage, diastolic and systolic dysfunction following acute myocardial injury due to bromine exposure in rats. (2021) Arch Toxicol. 95, 179-193 Pubmed Arch Toxicol PMC Article

Juncos JXM, Shakil S, Ahmad A, Aishah D, Morgan CJ, Dell'Italia LJ, Ford DA, Ahmad A and Ahmad S. Circulating and tissue biomarkers as predictors of bromine gas inhalation. (2020) Ann N Y Acad Sci. 1480, 104-115 Pubmed Ann N Y Acad Sci PMC Article

Aggarwal S, Lazrak A, Ahmad I, Yu Z, Bryant A, Mobley JA, Ford DA and Matalon S. Reactive species generated by heme impair alveolar epithelial sodium channel function in acute respiratory distress syndrome. (2020) Redox Biol. 36, 101592 Pubmed Redox Biol PMC Article

Yu H, Liu Y, Wang M, Restrepo RJ, Wang D, Kalogeris TJ, Neumann WL, Ford DA and Korthuis RJ. Myeloperoxidase instigates proinflammatory responses in a cecal ligation and puncture rat model of sepsis. (2020) Am J Physiol Heart Circ Physiol. 319, H705-H721 Pubmed Am J Physiol Heart Circ Physiol PMC Article

Addis DR, Aggarwal S, Doran SF, Jian MY, Ahmad I, Kojima K, Ford DA, Matalon S and Mobley JA. Vascular permeability disruption explored in the proteomes of mouse lungs and human microvascular cells following acute bromine exposure. (2020) Am J Physiol Lung Cell Mol Physiol. 319, L337-L359 Pubmed Am J Physiol Lung Cell Mol Physiol PMC Article

Petroff JT, Isor A, Chintala SM, Albert CJ, Franke JD, Weinstein D, Omlid SM, Arnatt CK, Ford DA and McCulla RD. oxidations of low-density lipoprotein and RAW 264.7 cells with lipophilic O(P)-precursors. (2020) RSC Adv. 10, 26553-26565 Pubmed RSC Adv PMC Article

Maner-Smith KM, Goll JB, Khadka M, Jensen TL, Colucci JK, Gelber CE, Albert CJ, Bosinger SE, Franke JD, Natrajan M, Rouphael N, Johnson RA, Sanz P, Anderson EJ, Hoft DF, Mulligan MJ, Ford DA and Ortlund EA. Alterations in the Human Plasma Lipidome in Response to Tularemia Vaccination. (2020) Vaccines (Basel). 8, Pubmed Vaccines (Basel) PMC Article

Pike DP, Vogel MJ, McHowat J, Mikuzis PA, Schulte KA and Ford DA. 2-Chlorofatty acids are biomarkers of sepsis mortality and mediators of barrier dysfunction in rats. (2020) J Lipid Res. 61, 1115-1127 Pubmed J Lipid Res PMC Article

Sur S, Nakanishi H, Flaveny C, Ippolito JE, McHowat J, Ford DA and Ray RB. Correction to: Inhibition of the key metabolic pathways, glycolysis and lipogenesis, of oral cancer by bitter melon extract. (2019) Cell Commun Signal. 17, 151 Pubmed Cell Commun Signal PMC Article

Sur S, Nakanishi H, Flaveny C, Ippolito JE, McHowat J, Ford DA and Ray RB. Inhibition of the key metabolic pathways, glycolysis and lipogenesis, of oral cancer by bitter melon extract. (2019) Cell Commun Signal. 17, 131 Pubmed Cell Commun Signal PMC Article

Shukla SD, Restrepo R, Aroor AR, Liu X, Lim RW, Franke JD, Ford DA and Korthuis RJ. Binge Alcohol Is More Injurious to Liver in Female than in Male Rats: Histopathological, Pharmacologic, and Epigenetic Profiles. (2019) J Pharmacol Exp Ther. 370, 390-398 Pubmed J Pharmacol Exp Ther PMC Article

Aggarwal S, Jilling T, Doran S, Ahmad I, Eagen JE, Gu S, Gillespie M, Albert CJ, Ford D, Oh JY, Patel RP and Matalon S. Phosgene inhalation causes hemolysis and acute lung injury. (2019) Toxicol Lett. 312, 204-213 Pubmed Toxicol Lett PMC Article

Olver TD, Edwards JC, Jurrissen TJ, Veteto AB, Jones JL, Gao C, Rau C, Warren CM, Klutho PJ, Alex L, Ferreira-Nichols SC, Ivey JR, Thorne PK, McDonald KS, Krenz M, Baines CP, Solaro RJ, Wang Y, Ford DA, Domeier TL, Padilla J, Rector RS and Emter CA. Western Diet-Fed, Aortic-Banded Ossabaw Swine: A Preclinical Model of Cardio-Metabolic Heart Failure. (2019) JACC Basic Transl Sci. 4, 404-421 Pubmed JACC Basic Transl Sci PMC Article

Zhang Q, Higginbotham JN, Jeppesen DK, Yang YP, Li W, McKinley ET, Graves-Deal R, Ping J, Britain CM, Dorsett KA, Hartman CL, Ford DA, Allen RM, Vickers KC, Liu Q, Franklin JL, Bellis SL and Coffey RJ. Transfer of Functional Cargo in Exomeres. (2019) Cell Rep. 27, 940-954.e6 Pubmed Cell Rep PMC Article

Kreienkamp R, Billon C, Bedia-Diaz G, Albert CJ, Toth Z, Butler AA, McBride-Gagyi S, Ford DA, Baldan A, Burris TP and Gonzalo S. Doubled lifespan and patient-like pathologies in progeria mice fed high-fat diet. (2019) Aging Cell. 18, e12852 Pubmed Aging Cell PMC Article

Yu H, Wang M, Wang D, Kalogeris TJ, McHowat J, Ford DA and Korthuis RJ. Chlorinated Lipids Elicit Inflammatory Responses in vitro and in vivo. (2019) Shock. 51, 114-122 Pubmed Shock PMC Article

Li L, Liu X, Sanders KL, Edwards JL, Ye J, Si F, Gao A, Huang L, Hsueh EC, Ford DA, Hoft DF and Peng G. TLR8-Mediated Metabolic Control of Human Treg Function: A Mechanistic Target for Cancer Immunotherapy. (2019) Cell Metab. 29, 103-123.e5 Pubmed Cell Metab PMC Article

Ahmad S, Masjoan Juncos JX, Ahmad A, Zaky A, Wei CC, Bradley WE, Zafar I, Powell P, Mariappan N, Vetal N, Louch WE, Ford DA, Doran SF, Matalon S and Dell'Italia LJ. Bromine inhalation mimics ischemia-reperfusion cardiomyocyte injury and calpain activation in rats. (2019) Am J Physiol Heart Circ Physiol. 316, H212-H223 Pubmed Am J Physiol Heart Circ Physiol PMC Article

Shim SH, Sur S, Steele R, Albert CJ, Huang C, Ford DA and Ray RB. Disrupting cholesterol esterification by bitter melon suppresses triple-negative breast cancer cell growth. (2018) Mol Carcinog. 57, 1599-1607 Pubmed Mol Carcinog

Sandhu J, Li S, Fairall L, Pfisterer SG, Gurnett JE, Xiao X, Weston TA, Vashi D, Ferrari A, Orozco JL, Hartman CL, Strugatsky D, Lee SD, He C, Hong C, Jiang H, Bentolila LA, Gatta AT, Levine TP, Ferng A, Lee R, Ford DA, Young SG, Ikonen E, Schwabe JWR and Tontonoz P. Aster Proteins Facilitate Nonvesicular Plasma Membrane to ER Cholesterol Transport in Mammalian Cells. (2018) Cell. 175, 514-529.e20 Pubmed Cell PMC Article

Palladino END, Katunga LA, Kolar GR and Ford DA. 2-Chlorofatty acids: lipid mediators of neutrophil extracellular trap formation. (2018) J Lipid Res. 59, 1424-1432 Pubmed J Lipid Res PMC Article

Hartman CL and Ford DA. MPO (Myeloperoxidase) Caused Endothelial Dysfunction. (2018) Arterioscler Thromb Vasc Biol. 38, 1676-1677 Pubmed Arterioscler Thromb Vasc Biol PMC Article

Courtney KC, Pezeshkian W, Raghupathy R, Zhang C, Darbyson A, Ipsen JH, Ford DA, Khandelia H, Presley JF and Zha X. C24 Sphingolipids Govern the Transbilayer Asymmetry of Cholesterol and Lateral Organization of Model and Live-Cell Plasma Membranes. (2018) Cell Rep. 24, 1037-1049 Pubmed Cell Rep

He C, Weston TA, Jung RS, Heizer P, Larsson M, Hu X, Allan CM, Tontonoz P, Reue K, Beigneux AP, Ploug M, Holme A, Kilburn M, Guagliardo P, Ford DA, Fong LG, Young SG and Jiang H. NanoSIMS Analysis of Intravascular Lipolysis and Lipid Movement across Capillaries and into Cardiomyocytes. (2018) Cell Metab. 27, 1055-1066.e3 Pubmed Cell Metab PMC Article

Duerr MA, Palladino END, Hartman CL, Lambert JA, Franke JD, Albert CJ, Matalon S, Patel RP, Slungaard A and Ford DA. Bromofatty aldehyde derived from bromine exposure and myeloperoxidase and eosinophil peroxidase modify GSH and protein. (2018) J Lipid Res. 59, 696-705 Pubmed J Lipid Res PMC Article

Palladino END, Hartman CL, Albert CJ and Ford DA. The chlorinated lipidome originating from myeloperoxidase-derived HOCl targeting plasmalogens: Metabolism, clearance, and biological properties. (2018) Arch Biochem Biophys. 641, 31-38 Pubmed Arch Biochem Biophys PMC Article

Wang B, Rong X, Palladino END, Wang J, Fogelman AM, Martín MG, Alrefai WA, Ford DA and Tontonoz P. Phospholipid Remodeling and Cholesterol Availability Regulate Intestinal Stemness and Tumorigenesis. (2018) Cell Stem Cell. 22, 206-220.e4 Pubmed Cell Stem Cell PMC Article

Hartman CL, Duerr MA, Albert CJ, Neumann WL, McHowat J and Ford DA. 2-Chlorofatty acids induce Weibel-Palade body mobilization. (2018) J Lipid Res. 59, 113-122 Pubmed J Lipid Res PMC Article

Meyer NJ, Reilly JP, Feng R, Christie JD, Hazen SL, Albert CJ, Franke JD, Hartman CL, McHowat J and Ford DA. Myeloperoxidase-derived 2-chlorofatty acids contribute to human sepsis mortality via acute respiratory distress syndrome. (2017) JCI Insight. 2, Pubmed JCI Insight PMC Article

Price NL, Rotllan N, Canfrán-Duque A, Zhang X, Pati P, Arias N, Moen J, Mayr M, Ford DA, Baldán Á, Suárez Y and Fernández-Hernando C. Genetic Dissection of the Impact of miR-33a and miR-33b during the Progression of Atherosclerosis. (2017) Cell Rep. 21, 1317-1330 Pubmed Cell Rep PMC Article

Rong X, Wang B, Palladino EN, de Aguiar Vallim TQ, Ford DA and Tontonoz P. ER phospholipid composition modulates lipogenesis during feeding and in obesity. (2017) J Clin Invest. 127, 3640-3651 Pubmed J Clin Invest PMC Article

Lambert JA, Carlisle MA, Lam A, Aggarwal S, Doran S, Ren C, Bradley WE, Dell'Italia L, Ambalavanan N, Ford DA, Patel RP, Jilling T and Matalon S. Mechanisms and Treatment of Halogen Inhalation-Induced Pulmonary and Systemic Injuries in Pregnant Mice. (2017) Hypertension. 70, 390-400 Pubmed Hypertension PMC Article

Wang HH, Li T, Portincasa P, Ford DA, Neuschwander-Tetri BA, Tso P and Wang DQ. New insights into the role of genes in the formation of cholesterol-supersaturated bile. (2017) Liver Res. 1, 42-53 Pubmed Liver Res PMC Article

de Aguiar Vallim TQ, Lee E, Merriott DJ, Goulbourne CN, Cheng J, Cheng A, Gonen A, Allen RM, Palladino END, Ford DA, Wang T, Baldán Á and Tarling EJ. ABCG1 regulates pulmonary surfactant metabolism in mice and men. (2017) J Lipid Res. 58, 941-954 Pubmed J Lipid Res PMC Article

Palladino EN, Wang WY, Albert CJ, Langhi C, Baldán Á and Ford DA. Peroxisome proliferator-activated receptor-α accelerates α-chlorofatty acid catabolism. (2017) J Lipid Res. 58, 317-324 Pubmed J Lipid Res PMC Article

Pike DP, Hartman CL, Weissler GJ, Palladino EN, Albert CJ and Ford DA. Platelet-Activating Factor Quantification Using Reversed Phase Liquid Chromatography and Selected Reaction Monitoring in Negative Ion Mode. (2016) Lipids. 51, 1421-1425 Pubmed Lipids PMC Article

Ford DA, Honavar J, Albert CJ, Duerr MA, Oh JY, Doran S, Matalon S and Patel RP. Formation of chlorinated lipids post-chlorine gas exposure. (2016) J Lipid Res. 57, 1529-40 Pubmed J Lipid Res PMC Article

Curtis C, Landis GN, Folk D, Wehr NB, Hoe N, Waskar M, Abdueva D, Skvortsov D, Ford D, Luu A, Badrinath A, Levine RL, Bradley TJ, Tavaré S and Tower J. Erratum to: Transcriptional profiling of MnSOD-mediated lifespan extension in Drosophila reveals a species-general network of aging and metabolic genes. (2016) Genome Biol. 17, 93 Pubmed Genome Biol PMC Article

Pauta M, Rotllan N, Fernández-Hernando A, Langhi C, Ribera J, Lu M, Boix L, Bruix J, Jimenez W, Suárez Y, Ford DA, Baldán A, Birnbaum MJ, Morales-Ruiz M and Fernández-Hernando C. Akt-mediated foxo1 inhibition is required for liver regeneration. (2016) Hepatology. 63, 1660-74 Pubmed Hepatology PMC Article

Wang B, Rong X, Duerr MA, Hermanson DJ, Hedde PN, Wong JS, Vallim TQ, Cravatt BF, Gratton E, Ford DA and Tontonoz P. Intestinal Phospholipid Remodeling Is Required for Dietary-Lipid Uptake and Survival on a High-Fat Diet. (2016) Cell Metab. 23, 492-504 Pubmed Cell Metab PMC Article

Aroor AR, Habibi J, Ford DA, Nistala R, Lastra G, Manrique C, Dunham MM, Ford KD, Thyfault JP, Parks EJ, Sowers JR and Rector RS. Dipeptidyl peptidase-4 inhibition ameliorates Western diet-induced hepatic steatosis and insulin resistance through hepatic lipid remodeling and modulation of hepatic mitochondrial function. (2015) Diabetes. 64, 1988-2001 Pubmed Diabetes PMC Article

Duerr MA, Aurora R and Ford DA. Identification of glutathione adducts of α-chlorofatty aldehydes produced in activated neutrophils. (2015) J Lipid Res. 56, 1014-24 Pubmed J Lipid Res PMC Article

Alsufiani HM, Yamani F, Kumosani TA, Ford D and Mathers JC. The relative validity and repeatability of an FFQ for estimating intake of zinc and its absorption modifiers in young and older Saudi adults. (2015) Public Health Nutr. 18, 968-76 Pubmed Public Health Nutr PMC Article

Shih DM, Yu JM, Vergnes L, Dali-Youcef N, Champion MD, Devarajan A, Zhang P, Castellani LW, Brindley DN, Jamey C, Auwerx J, Reddy ST, Ford DA, Reue K and Lusis AJ. PON3 knockout mice are susceptible to obesity, gallstone formation, and atherosclerosis. (2015) FASEB J. 29, 1185-97 Pubmed FASEB J PMC Article

Rong X, Wang B, Dunham MM, Hedde PN, Wong JS, Gratton E, Young SG, Ford DA and Tontonoz P. Lpcat3-dependent production of arachidonoyl phospholipids is a key determinant of triglyceride secretion. (2015) Elife. 4, Pubmed Elife PMC Article

Baldan A, Gonen A, Choung C, Que X, Marquart TJ, Hernandez I, Bjorkhem I, Ford DA, Witztum JL and Tarling EJ. ABCG1 is required for pulmonary B-1 B cell and natural antibody homeostasis. (2014) J Immunol. 193, 5637-48 Pubmed J Immunol PMC Article

Soufi N, Hall AM, Chen Z, Yoshino J, Collier SL, Mathews JC, Brunt EM, Albert CJ, Graham MJ, Ford DA and Finck BN. Inhibiting monoacylglycerol acyltransferase 1 ameliorates hepatic metabolic abnormalities but not inflammation and injury in mice. (2014) J Biol Chem. 289, 30177-88 Pubmed J Biol Chem PMC Article

Mahieu MA, Guild CP, Albert CJ, Kondos GT, Carr JJ, Edmundowicz D, Ford DA and Ramsey-Goldman R. Alpha-chlorofatty Acid and coronary artery or aorta calcium scores in women with systemic lupus erythematosus. A pilot study. (2014) J Rheumatol. 41, 1834-42 Pubmed J Rheumatol PMC Article

Yang Y, Kuwano T, Lagor WR, Albert CJ, Brenton S, Rader DJ, Ford DA and Brown RJ. Lipidomic analyses of female mice lacking hepatic lipase and endothelial lipase indicate selective modulation of plasma lipid species. (2014) Lipids. 49, 505-15 Pubmed Lipids PMC Article

Shao F and Ford DA. Elaidic acid increases hepatic lipogenesis by mediating sterol regulatory element binding protein-1c activity in HuH-7 cells. (2014) Lipids. 49, 403-13 Pubmed Lipids PMC Article

Wang WY, Albert CJ and Ford DA. Alpha-chlorofatty acid accumulates in activated monocytes and causes apoptosis through reactive oxygen species production and endoplasmic reticulum stress. (2014) Arterioscler Thromb Vasc Biol. 34, 526-32 Pubmed Arterioscler Thromb Vasc Biol PMC Article

Wang WY, Albert CJ and Ford DA. Approaches for the analysis of chlorinated lipids. (2013) Anal Biochem. 443, 148-52 Pubmed Anal Biochem PMC Article

Shao F and Ford DA. Differential regulation of ABCA1 and macrophage cholesterol efflux by elaidic and oleic acids. (2013) Lipids. 48, 757-67 Pubmed Lipids PMC Article

Essaji Y, Yang Y, Albert CJ, Ford DA and Brown RJ. Hydrolysis products generated by lipoprotein lipase and endothelial lipase differentially impact THP-1 macrophage cell signalling pathways. (2013) Lipids. 48, 769-778 Pubmed Lipids PMC Article

Wacker BK, Albert CJ, Ford BA and Ford DA. Strategies for the analysis of chlorinated lipids in biological systems. (2013) Free Radic Biol Med. 59, 92-9 Pubmed Free Radic Biol Med PMC Article

Rubinow KB, Wall VZ, Nelson J, Mar D, Bomsztyk K, Askari B, Lai MA, Smith KD, Han MS, Vivekanandan-Giri A, Pennathur S, Albert CJ, Ford DA, Davis RJ and Bornfeldt KE. Acyl-CoA synthetase 1 is induced by Gram-negative bacteria and lipopolysaccharide and is required for phospholipid turnover in stimulated macrophages. (2013) J Biol Chem. 288, 9957-9970 Pubmed J Biol Chem PMC Article

Brown RJ, Shao F, Baldán A, Albert CJ and Ford DA. Cholesterol efflux analyses using stable isotopes and mass spectrometry. (2013) Anal Biochem. 433, 56-64 Pubmed Anal Biochem PMC Article

Allen RM, Marquart TJ, Albert CJ, Suchy FJ, Wang DQ, Ananthanarayanan M, Ford DA and Baldán A. miR-33 controls the expression of biliary transporters, and mediates statin- and diet-induced hepatotoxicity. (2012) EMBO Mol Med. 4, 882-95 Pubmed EMBO Mol Med PMC Article

Bowden JA, Shao F, Albert CJ, Lally JW, Brown RJ, Procknow JD, Stephenson AH and Ford DA. Electrospray ionization tandem mass spectrometry of sodiated adducts of cholesteryl esters. (2011) Lipids. 46, 1169-79 Pubmed Lipids PMC Article

Bowden JA, Albert CJ, Barnaby OS and Ford DA. Analysis of cholesteryl esters and diacylglycerols using lithiated adducts and electrospray ionization-tandem mass spectrometry. (2011) Anal Biochem. 417, 202-10 Pubmed Anal Biochem PMC Article

Clark EA, Walker N, Ford DC, Cooper IA, Oyston PC and Acharya KR. Molecular recognition of chymotrypsin by the serine protease inhibitor ecotin from Yersinia pestis. (2011) J Biol Chem. 286, 24015-22 Pubmed J Biol Chem PMC Article

Bowden JA and Ford DA. An examination of pentafluorobenzoyl derivatization strategies for the analysis of fatty alcohols using gas chromatography/electron capture negative ion chemical ionization-mass spectrometry. (2011) J Chromatogr B Analyt Technol Biomed Life Sci. 879, 1375-83 Pubmed J Chromatogr B Analyt Technol Biomed Life Sci PMC Article

Brahmbhatt VV, Albert CJ, Anbukumar DS, Cunningham BA, Neumann WL and Ford DA. {Omega}-oxidation of {alpha}-chlorinated fatty acids: identification of {alpha}-chlorinated dicarboxylic acids. (2010) J Biol Chem. 285, 41255-69 Pubmed J Biol Chem PMC Article

Ford DA. Lipid oxidation by hypochlorous acid: chlorinated lipids in atherosclerosis and myocardial ischemia. (2010) Clin Lipidol. 5, 835-852 Pubmed Clin Lipidol PMC Article

Anbukumar DS, Shornick LP, Albert CJ, Steward MM, Zoeller RA, Neumann WL and Ford DA. Chlorinated lipid species in activated human neutrophils: lipid metabolites of 2-chlorohexadecanal. (2010) J Lipid Res. 51, 1085-92 Pubmed J Lipid Res PMC Article

Albert CJ, Anbukumar DS, Messner MC and Ford DA. Chromatographic methods for the analyses of 2-halofatty aldehydes and chlorohydrin molecular species of lysophosphatidylcholine. (2009) J Chromatogr B Analyt Technol Biomed Life Sci. 877, 2768-77 Pubmed J Chromatogr B Analyt Technol Biomed Life Sci PMC Article

Lankalapalli RS, Eckelkamp JT, Sircar D, Ford DA, Subbaiah PV and Bittman R. Synthesis and antioxidant properties of an unnatural plasmalogen analogue bearing a trans O-vinyl ether linkage. (2009) Org Lett. 11, 2784-7 Pubmed Org Lett PMC Article

Messner MC, Albert CJ and Ford DA. 2-Chlorohexadecanal and 2-chlorohexadecanoic acid induce COX-2 expression in human coronary artery endothelial cells. (2008) Lipids. 43, 581-8 Pubmed Lipids PMC Article

Ford DA, Monda JK, Brush RS, Anderson RE, Richards MJ and Fliesler SJ. Lipidomic analysis of the retina in a rat model of Smith-Lemli-Opitz syndrome: alterations in docosahexaenoic acid content of phospholipid molecular species. (2008) J Neurochem. 105, 1032-47 Pubmed J Neurochem PMC Article

Messner MC, Albert CJ, McHowat J and Ford DA. Identification of lysophosphatidylcholine-chlorohydrin in human atherosclerotic lesions. (2008) Lipids. 43, 243-9 Pubmed Lipids PMC Article

Brahmbhatt VV, Nold C, Albert CJ and Ford DA. Quantification of pentafluorobenzyl oxime derivatives of long chain aldehydes by GC-MS analysis. (2008) Lipids. 43, 275-80 Pubmed Lipids PMC Article

Brahmbhatt VV, Hsu FF, Kao JL, Frank EC and Ford DA. Novel carbonyl and nitrile products from reactive chlorinating species attack of lysosphingolipid. (2007) Chem Phys Lipids. 145, 72-84 Pubmed Chem Phys Lipids

Albert CJ, Anbukumar DS, Monda JK, Eckelkamp JT and Ford DA. Myocardial lipidomics. Developments in myocardial nuclear lipidomics. (2007) Front Biosci. 12, 2750-60 Pubmed Front Biosci PMC Article

Chandrasekaran S, Deffenbaugh AE, Ford DA, Bailly E, Mathias N and Skowyra D. Destabilization of binding to cofactors and SCFMet30 is the rate-limiting regulatory step in degradation of polyubiquitinated Met4. (2006) Mol Cell. 24, 689-699 Pubmed Mol Cell

Messner MC, Albert CJ, Hsu FF and Ford DA. Selective plasmenylcholine oxidation by hypochlorous acid: formation of lysophosphatidylcholine chlorohydrins. (2006) Chem Phys Lipids. 144, 34-44 Pubmed Chem Phys Lipids

Wildsmith KR, Albert CJ, Anbukumar DS and Ford DA. Metabolism of myeloperoxidase-derived 2-chlorohexadecanal. (2006) J Biol Chem. 281, 16849-16860 Pubmed J Biol Chem

Wildsmith KR, Albert CJ, Hsu FF, Kao JL and Ford DA. Myeloperoxidase-derived 2-chlorohexadecanal forms Schiff bases with primary amines of ethanolamine glycerophospholipids and lysine. (2006) Chem Phys Lipids. 139, 157-70 Pubmed Chem Phys Lipids

Thukkani AK, Martinson BD, Albert CJ, Vogler GA and Ford DA. Neutrophil-mediated accumulation of 2-ClHDA during myocardial infarction: 2-ClHDA-mediated myocardial injury. (2005) Am J Physiol Heart Circ Physiol. 288, H2955-64 Pubmed Am J Physiol Heart Circ Physiol

Thukkani AK, McHowat J, Hsu FF, Brennan ML, Hazen SL and Ford DA. Identification of alpha-chloro fatty aldehydes and unsaturated lysophosphatidylcholine molecular species in human atherosclerotic lesions. (2003) Circulation. 108, 3128-33 Pubmed Circulation

Martinson BD, Albert CJ, Corbett JA, Wysolmerski RB and Ford DA. Calcium-independent phospholipase A2 mediates CREB phosphorylation in double-stranded RNA-stimulated endothelial cells. (2003) J Lipid Res. 44, 1686-91 Pubmed J Lipid Res

Thukkani AK, Albert CJ, Wildsmith KR, Messner MC, Martinson BD, Hsu FF and Ford DA. Myeloperoxidase-derived reactive chlorinating species from human monocytes target plasmalogens in low density lipoprotein. (2003) J Biol Chem. 278, 36365-72 Pubmed J Biol Chem

Albert CJ, Thukkani AK, Heuertz RM, Slungaard A, Hazen SL and Ford DA. Eosinophil peroxidase-derived reactive brominating species target the vinyl ether bond of plasmalogens generating a novel chemoattractant, alpha-bromo fatty aldehyde. (2003) J Biol Chem. 278, 8942-50 Pubmed J Biol Chem

Ford DA. Separate myocardial ethanolamine phosphotransferase activities responsible for plasmenylethanolamine and phosphatidylethanolamine synthesis. (2003) J Lipid Res. 44, 554-9 Pubmed J Lipid Res

Steer SA, Wirsig KC, Creer MH, Ford DA and McHowat J. Regulation of membrane-associated iPLA2 activity by a novel PKC isoform in ventricular myocytes. (2002) Am J Physiol Cell Physiol. 283, C1621-6 Pubmed Am J Physiol Cell Physiol

Maggi LB, Moran JM, Scarim AL, Ford DA, Yoon JW, McHowat J, Buller RM and Corbett JA. Novel role for calcium-independent phospholipase A(2) in the macrophage antiviral response of inducible nitric-oxide synthase expression. (2002) J Biol Chem. 277, 38449-55 Pubmed J Biol Chem

Thukkani AK, Hsu FF, Crowley JR, Wysolmerski RB, Albert CJ and Ford DA. Reactive chlorinating species produced during neutrophil activation target tissue plasmalogens: production of the chemoattractant, 2-chlorohexadecanal. (2002) J Biol Chem. 277, 3842-9 Pubmed J Biol Chem

Albert CJ, Crowley JR, Hsu FF, Thukkani AK and Ford DA. Reactive brominating species produced by myeloperoxidase target the vinyl ether bond of plasmalogens: disparate utilization of sodium halides in the production of alpha-halo fatty aldehydes. (2002) J Biol Chem. 277, 4694-703 Pubmed J Biol Chem

Ford DA. Alterations in myocardial lipid metabolism during myocardial ischemia and reperfusion. (2002) Prog Lipid Res. 41, 6-26 Pubmed Prog Lipid Res

Venkatachalam K, Ma HT, Ford DL and Gill DL. Expression of functional receptor-coupled TRPC3 channels in DT40 triple receptor InsP3 knockout cells. (2001) J Biol Chem. 276, 33980-5 Pubmed J Biol Chem

Williams SD and Ford DA. Calcium-independent phospholipase A(2) mediates CREB phosphorylation and c-fos expression during ischemia. (2001) Am J Physiol Heart Circ Physiol. 281, H168-76 Pubmed Am J Physiol Heart Circ Physiol

Albert CJ, Crowley JR, Hsu FF, Thukkani AK and Ford DA. Reactive chlorinating species produced by myeloperoxidase target the vinyl ether bond of plasmalogens: identification of 2-chlorohexadecanal. (2001) J Biol Chem. 276, 23733-41 Pubmed J Biol Chem

Williams SD, Hsu FF and Ford DA. Electrospray ionization mass spectrometry analyses of nuclear membrane phospholipid loss after reperfusion of ischemic myocardium. (2000) J Lipid Res. 41, 1585-95 Pubmed J Lipid Res

Albert CJ and Ford DA. Protein kinase C translocation and PKC-dependent protein phosphorylation during myocardial ischemia. (1999) Am J Physiol. 276, H642-50 Pubmed Am J Physiol

Albert CJ and Ford DA. Identification of specific nuclear protein kinase C isozymes and accelerated protein kinase C-dependent nuclear protein phosphorylation during myocardial ischemia. (1998) FEBS Lett. 438, 32-6 Pubmed FEBS Lett

Ford DA, Horner CC and Gross RW. Protein kinase C acylation by palmitoyl coenzyme A facilitates its translocation to membranes. (1998) Biochemistry. 37, 11953-61 Pubmed Biochemistry

Hale CC, Ebeling EG, Hsu FF and Ford DA. The selective activation of the cardiac sarcolemmal sodium-calcium exchanger by plasmalogenic phosphatidic acid produced by phospholipase D. (1998) FEBS Lett. 422, 247-51 Pubmed FEBS Lett

Williams SD and Ford DA. Activation of myocardial cAMP-dependent protein kinase by lysoplasmenylcholine. (1997) FEBS Lett. 420, 33-8 Pubmed FEBS Lett

Ford DA and Hale CC. Plasmalogen and anionic phospholipid dependence of the cardiac sarcolemmal sodium-calcium exchanger. (1996) FEBS Lett. 394, 99-102 Pubmed FEBS Lett

Hazen SL, Ford DA and Gross RW. Activation of a membrane-associated phospholipase A2 during rabbit myocardial ischemia which is highly selective for plasmalogen substrate. (1991) J Biol Chem. 266, 5629-33 Pubmed J Biol Chem

Ford DA and Gross RW. Differential metabolism of diradyl glycerol molecular subclasses and molecular species by rabbit brain diglyceride kinase. (1990) J Biol Chem. 265, 12280-6 Pubmed J Biol Chem

Ford DA and Gross RW. Activation of myocardial protein kinase C by plasmalogenic diglycerides. (1990) Am J Physiol. 258, C30-6 Pubmed Am J Physiol

Ford DB and Benson AM. Differential responses of mouse UDP-glucuronosyltransferases and beta-glucuronidase to disulfiram and related compounds. (1988) Biochem Biophys Res Commun. 153, 149-55 Pubmed Biochem Biophys Res Commun

Phillips S, Cantrill R, Ford D and Mitchell D. Microinjection of dopamine agonists into nucleus raphe magnus affects nociception in rats. (1986) Pain. 26, 259-266 Pubmed Pain

Meatherall R and Ford D. Isocratic liquid chromatographic determination of theophylline, acetaminophen, chloramphenicol, caffeine, anticonvulsants, and barbiturates in serum. (1988) Ther Drug Monit. 10, 101-15 Pubmed Ther Drug Monit

McHowat J, Shakya S and Ford DA. 2-Chlorofatty Aldehyde Elicits Endothelial Cell Activation. (2020) Front Physiol. 11, 460 Pubmed Front Physiol PMC Article

Amunugama K, Kolar GR and Ford DA. Neutrophil Myeloperoxidase Derived Chlorolipid Production During Bacteria Exposure. (2021) Front Immunol. 12, 701227 Pubmed Front Immunol PMC Article

Amunugama K, Pike DP and Ford DA. The lipid biology of sepsis. (2021) J Lipid Res. 62, 100090 Pubmed J Lipid Res PMC Article

Amunugama K, Pike DP and Ford DA. strain-dependent lipid alterations in cocultures with endothelial cells and neutrophils modeling sepsis. (2022) Front Physiol. 13, 980460 Pubmed Front Physiol PMC Article

Pike DP, McGuffee RM, Geerling E, Albert CJ, Hoft DF, Shashaty MGS, Meyer NJ, Pinto AK and Ford DA. Plasmalogen Loss in Sepsis and SARS-CoV-2 Infection. (2022) Front Cell Dev Biol. 10, 912880 Pubmed Front Cell Dev Biol PMC Article

Davis MB, Walens A, Hire R, Mumin K, Brown AM, Ford D, Howerth EW and Monteil M. Distinct Transcript Isoforms of the Atypical Chemokine Receptor 1 (ACKR1)/Duffy Antigen Receptor for Chemokines (DARC) Gene Are Expressed in Lymphoblasts and Altered Isoform Levels Are Associated with Genetic Ancestry and the Duffy-Null Allele. (2015) PLoS One. 10, e0140098 Pubmed PLoS One PMC Article

Maness PF, Cone GW, Ford DA and McCulla RD. Comparison of Low-Density Lipoprotein Oxidation by Hydrophilic O( P)-Precursors and Lipid-O( P)-Precursor Conjugates. (2023) Photochem Photobiol. 99, 1412-1419 Pubmed Photochem Photobiol

Sharpe MC, Pyles KD, Hallcox T, Kamm DR, Piechowski M, Fisk B, Albert CJ, Carpenter DH, Ulmasov B, Ford DA, Neuschwander-Tetri BA and McCommis KS. Enhancing Hepatic MBOAT7 Expression in Mice With Nonalcoholic Steatohepatitis. (2023) Gastro Hep Adv. 2, 558-572 Pubmed Gastro Hep Adv PMC Article

Balogun KA, Albert CJ, Ford DA, Brown RJ and Cheema SK. Dietary omega-3 polyunsaturated fatty acids alter the fatty acid composition of hepatic and plasma bioactive lipids in C57BL/6 mice: a lipidomic approach. (2013) PLoS One. 8, e82399 Pubmed PLoS One PMC Article

Ford DA. A BOSSS platform: using functionalized lipids and click chemistry for new discoveries in lipid research. (2021) J Lipid Res. 62, 100025 Pubmed J Lipid Res PMC Article