Education and Lab Experience

  • Research Scientist, Saint Louis University Department of Biochemistry and Molecular Biology (2018-present)
  • Senior Scientist, Washington University in St. Louis (2011-2018)
  • Postdoctoral Fellow, Washington University in St. Louis (2006-2011)
  • Ph.D., Molecular Basis of Disease, Medical University of Ohio at Toledo (2006)
  • M.S., Clinical Laboratory Sciences, Michigan State University (2001)

Publications

Smith-Tsurkan SD, Herr RA, Khuder S, Wilke CO and Novella IS. The role of environmental factors on the evolution of phenotypic diversity in vesicular stomatitis virus populations. (2013) J. Gen. Virol.. 94, 860-8 Pubmed J. Gen. Virol. PMC Article
Herr RA, Wang X, Loh J, Virgin HW and Hansen TH. Newly discovered viral E3 ligase pK3 induces endoplasmic reticulum-associated degradation of class I major histocompatibility proteins and their membrane-bound chaperones. (2012) J. Biol. Chem.. 287, 14467-79 Pubmed J. Biol. Chem. PMC Article
Wang X, Herr RA and Hansen TH. Ubiquitination of substrates by esterification. (2012) Traffic. 13, 19-24 Pubmed Traffic PMC Article
Wang X, Herr RA, Rabelink M, Hoeben RC, Wiertz EJ and Hansen TH. Ube2j2 ubiquitinates hydroxylated amino acids on ER-associated degradation substrates. (2009) J. Cell Biol.. 187, 655-68 Pubmed J. Cell Biol. PMC Article
Herr RA, Harris J, Fang S, Wang X and Hansen TH. Role of the RING-CH domain of viral ligase mK3 in ubiquitination of non-lysine and lysine MHC I residues. (2009) Traffic. 10, 1301-17 Pubmed Traffic
Wang X, Herr RA and Hansen T. Viral and cellular MARCH ubiquitin ligases and cancer. (2008) Semin. Cancer Biol.. 18, 441-50 Pubmed Semin. Cancer Biol. PMC Article
Herr RA, Hung CY and Cole GT. Evaluation of two homologous proline-rich proteins of Coccidioides posadasii as candidate vaccines against coccidioidomycosis. (2007) Infect. Immun.. 75, 5777-87 Pubmed Infect. Immun. PMC Article
Wang X, Herr RA, Chua WJ, Lybarger L, Wiertz EJ and Hansen TH. Ubiquitination of serine, threonine, or lysine residues on the cytoplasmic tail can induce ERAD of MHC-I by viral E3 ligase mK3. (2007) J. Cell Biol.. 177, 613-24 Pubmed J. Cell Biol. PMC Article
Shubitz LF, Yu JJ, Hung CY, Kirkland TN, Peng T, Perrill R, Simons J, Xue J, Herr RA, Cole GT and Galgiani JN. Improved protection of mice against lethal respiratory infection with Coccidioides posadasii using two recombinant antigens expressed as a single protein. (2006) Vaccine. 24, 5904-11 Pubmed Vaccine
Johannesson H, Vidal P, Guarro J, Herr RA, Cole GT and Taylor JW. Positive directional selection in the proline-rich antigen (PRA) gene among the human pathogenic fungi Coccidioides immitis, C. posadasii and their closest relatives. (2004) Mol. Biol. Evol.. 21, 1134-45 Pubmed Mol. Biol. Evol.
Cole GT, Xue JM, Okeke CN, Tarcha EJ, Basrur V, Schaller RA, Herr RA, Yu JJ and Hung CY. A vaccine against coccidioidomycosis is justified and attainable. (2004) Med. Mycol.. 42, 189-216 Pubmed Med. Mycol.
Herr RA, Tarcha EJ, Taborda PR, Taylor JW, Ajello L and Mendoza L. Phylogenetic analysis of Lacazia loboi places this previously uncharacterized pathogen within the dimorphic Onygenales. (2001) J. Clin. Microbiol.. 39, 309-14 Pubmed J. Clin. Microbiol. PMC Article
Herr RA, Ajello L, Taylor JW, Arseculeratne SN and Mendoza L. Phylogenetic analysis of Rhinosporidium seeberi's 18S small-subunit ribosomal DNA groups this pathogen among members of the protoctistan Mesomycetozoa clade. (1999) J. Clin. Microbiol.. 37, 2750-4 Pubmed J. Clin. Microbiol. PMC Article
Herr RA, Mendoza L, Arseculeratne SN and Ajello L. Immunolocalization of an endogenous antigenic material of Rhinosporidium seeberi expressed only during mature sporangial development. (1999) FEMS Immunol. Med. Microbiol.. 23, 205-12 Pubmed FEMS Immunol. Med. Microbiol.
Mendoza L, Herr RA, Arseculeratne SN and Ajello L. In vitro studies on the mechanisms of endospore release by Rhinosporidium seeberi. (1999) Mycopathologia. 148, 9-15 Pubmed Mycopathologia