Wilkie SE, Marcu DE, Carter RN, Morton NM, Gonzalo S and Selman C. Hepatic hydrogen sulfide levels are reduced in mouse model of Hutchinson-Gilford progeria syndrome. (2023) Aging (Albany NY). 15, 5266-5278 Pubmed Aging (Albany NY) PMC Article
Coll-Bonfill N, Mahajan U, Shashkova EV, Lin CJ, Mecham RP and Gonzalo S. Progerin induces a phenotypic switch in vascular smooth muscle cells and triggers replication stress and an aging-associated secretory signature. (2023) Geroscience. 45, 965-982 Pubmed Geroscience PMC Article
Graziano S, Coll-Bonfill N, Teodoro-Castro B, Kuppa S, Jackson J, Shashkova E, Mahajan U, Vindigni A, Antony E and Gonzalo S. Lamin A/C recruits ssDNA protective proteins RPA and RAD51 to stalled replication forks to maintain fork stability. (2021) J Biol Chem. 297, 101301 Pubmed J Biol Chem PMC Article
Vidal S, Sánchez-Aparicio M, Seoane R, El Motiam A, Nelson EV, Bouzaher YH, Baz-Martínez M, García-Dorival I, Gonzalo S, Vázquez E, Vidal A, Muñoz-Fontela C, García-Sastre A and Rivas C. Expression of the Ebola Virus VP24 Protein Compromises the Integrity of the Nuclear Envelope and Induces a Laminopathy-Like Cellular Phenotype. (2021) mBio. 12, e0097221 Pubmed mBio PMC Article
Eissenberg JC and Gonzalo S. Pushing the limit on laminopathies. (2020) Nat Mater. 19, 378-380 Pubmed Nat Mater PMC Article
Coll-Bonfill N, Cancado de Faria R, Bhoopatiraju S and Gonzalo S. Calcitriol Prevents RAD51 Loss and cGAS-STING-IFN Response Triggered by Progerin. (2020) Proteomics. 20, e1800406 Pubmed Proteomics PMC Article
Kreienkamp R and Gonzalo S. Metabolic Dysfunction in Hutchinson-Gilford Progeria Syndrome. (2020) Cells. 9, Pubmed Cells PMC Article
Maynard S, Keijzers G, Akbari M, Ezra MB, Hall A, Morevati M, Scheibye-Knudsen M, Gonzalo S, Bartek J and Bohr VA. Lamin A/C promotes DNA base excision repair. (2019) Nucleic Acids Res. 47, 11709-11728 Pubmed Nucleic Acids Res PMC Article
Gonzalo S and Coll-Bonfill N. Genomic instability and innate immune responses to self-DNA in progeria. (2019) Geroscience. 41, 255-266 Pubmed Geroscience PMC Article
Kreienkamp R, Billon C, Bedia-Diaz G, Albert CJ, Toth Z, Butler AA, McBride-Gagyi S, Ford DA, Baldan A, Burris TP and Gonzalo S. Doubled lifespan and patient-like pathologies in progeria mice fed high-fat diet. (2019) Aging Cell. 18, e12852 Pubmed Aging Cell PMC Article
Carvajal-Maldonado D, Byrum AK, Jackson J, Wessel S, Lemaçon D, Guitton-Sert L, Quinet A, Tirman S, Graziano S, Masson JY, Cortez D, Gonzalo S, Mosammaparast N and Vindigni A. Perturbing cohesin dynamics drives MRE11 nuclease-dependent replication fork slowing. (2019) Nucleic Acids Res. 47, 1294-1310 Pubmed Nucleic Acids Res PMC Article
Kreienkamp R, Graziano S, Coll-Bonfill N, Bedia-Diaz G, Cybulla E, Vindigni A, Dorsett D, Kubben N, Batista LFZ and Gonzalo S. A Cell-Intrinsic Interferon-like Response Links Replication Stress to Cellular Aging Caused by Progerin. (2018) Cell Rep. 22, 2006-2015 Pubmed Cell Rep PMC Article
Graziano S, Kreienkamp R, Coll-Bonfill N and Gonzalo S. Causes and consequences of genomic instability in laminopathies: Replication stress and interferon response. (2018) Nucleus. 9, 258-275 Pubmed Nucleus PMC Article
Graziano S and Gonzalo S. Mechanisms of oncogene-induced genomic instability. (2017) Biophys Chem. 225, 49-57 Pubmed Biophys Chem PMC Article
Gonzalo S, Kreienkamp R and Askjaer P. Hutchinson-Gilford Progeria Syndrome: A premature aging disease caused by LMNA gene mutations. (2017) Ageing Res Rev. 33, 18-29 Pubmed Ageing Res Rev PMC Article
Graziano S, Johnston R, Deng O, Zhang J and Gonzalo S. Vitamin D/vitamin D receptor axis regulates DNA repair during oncogene-induced senescence. (2016) Oncogene. 35, 5362-5376 Pubmed Oncogene PMC Article
Kreienkamp R, Croke M, Neumann MA, Bedia-Diaz G, Graziano S, Dusso A, Dorsett D, Carlberg C and Gonzalo S. Vitamin D receptor signaling improves Hutchinson-Gilford progeria syndrome cellular phenotypes. (2016) Oncotarget. 7, 30018-31 Pubmed Oncotarget PMC Article
Dobrzynska A, Gonzalo S, Shanahan C and Askjaer P. The nuclear lamina in health and disease. (2016) Nucleus. 7, 233-48 Pubmed Nucleus PMC Article
Gonzalo S and Eissenberg JC. Tying up loose ends: telomeres, genomic instability and lamins. (2016) Curr Opin Genet Dev. 37, 109-118 Pubmed Curr Opin Genet Dev PMC Article
Bronshtein I, Kepten E, Kanter I, Berezin S, Lindner M, Redwood AB, Mai S, Gonzalo S, Foisner R, Shav-Tal Y and Garini Y. Loss of lamin A function increases chromatin dynamics in the nuclear interior. (2015) Nat Commun. 6, 8044 Pubmed Nat Commun PMC Article
Gonzalo S and Kreienkamp R. DNA repair defects and genome instability in Hutchinson-Gilford Progeria Syndrome. (2015) Curr Opin Cell Biol. 34, 75-83 Pubmed Curr Opin Cell Biol PMC Article
Gonzalo S. Novel roles of 1α,25(OH)2D3 on DNA repair provide new strategies for breast cancer treatment. (2014) J Steroid Biochem Mol Biol. 144 Pt A, 59-64 Pubmed J Steroid Biochem Mol Biol PMC Article
Croke M, Neumann MA, Grotsky DA, Kreienkamp R, Yaddanapudi SC and Gonzalo S. Differences in 53BP1 and BRCA1 regulation between cycling and non-cycling cells. (2013) Cell Cycle. 12, 3629-39 Pubmed Cell Cycle PMC Article
Grotsky DA, Gonzalez-Suarez I, Novell A, Neumann MA, Yaddanapudi SC, Croke M, Martinez-Alonso M, Redwood AB, Ortega-Martinez S, Feng Z, Lerma E, Ramon y Cajal T, Zhang J, Matias-Guiu X, Dusso A and Gonzalo S. BRCA1 loss activates cathepsin L-mediated degradation of 53BP1 in breast cancer cells. (2013) J Cell Biol. 200, 187-202 Pubmed J Cell Biol PMC Article
Redwood AB, Gonzalez-Suarez I and Gonzalo S. Regulating the levels of key factors in cell cycle and DNA repair: new pathways revealed by lamins. (2011) Cell Cycle. 10, 3652-7 Pubmed Cell Cycle PMC Article
Redwood AB, Perkins SM, Vanderwaal RP, Feng Z, Biehl KJ, Gonzalez-Suarez I, Morgado-Palacin L, Shi W, Sage J, Roti-Roti JL, Stewart CL, Zhang J and Gonzalo S. A dual role for A-type lamins in DNA double-strand break repair. (2011) Cell Cycle. 10, 2549-60 Pubmed Cell Cycle PMC Article
Gonzalez-Suarez I, Redwood AB, Grotsky DA, Neumann MA, Cheng EH, Stewart CL, Dusso A and Gonzalo S. A new pathway that regulates 53BP1 stability implicates cathepsin L and vitamin D in DNA repair. (2011) EMBO J. 30, 3383-96 Pubmed EMBO J PMC Article
Chen H, Ma Z, Vanderwaal RP, Feng Z, Gonzalez-Suarez I, Wang S, Zhang J, Roti Roti JL, Gonzalo S and Zhang J. The mTOR inhibitor rapamycin suppresses DNA double-strand break repair. (2011) Radiat Res. 175, 214-24 Pubmed Radiat Res PMC Article
Shi W, Feng Z, Zhang J, Gonzalez-Suarez I, Vanderwaal RP, Wu X, Powell SN, Roti Roti JL, Gonzalo S and Zhang J. The role of RPA2 phosphorylation in homologous recombination in response to replication arrest. (2010) Carcinogenesis. 31, 994-1002 Pubmed Carcinogenesis PMC Article
Gonzalez-Suarez I, Redwood AB and Gonzalo S. Loss of A-type lamins and genomic instability. (2009) Cell Cycle. 8, 3860-5 Pubmed Cell Cycle
Gonzalez-Suarez I, Redwood AB, Perkins SM, Vermolen B, Lichtensztejin D, Grotsky DA, Morgado-Palacin L, Gapud EJ, Sleckman BP, Sullivan T, Sage J, Stewart CL, Mai S and Gonzalo S. Novel roles for A-type lamins in telomere biology and the DNA damage response pathway. (2009) EMBO J. 28, 2414-27 Pubmed EMBO J PMC Article
Zeng S, Xiang T, Pandita TK, Gonzalez-Suarez I, Gonzalo S, Harris CC and Yang Q. Telomere recombination requires the MUS81 endonuclease. (2009) Nat Cell Biol. 11, 616-23 Pubmed Nat Cell Biol PMC Article
Dahiya A, Wong S, Gonzalo S, Gavin M and Dean DC. Linking the Rb and polycomb pathways. (2001) Mol Cell. 8, 557-69 Pubmed Mol Cell
Gonzalo S, Greentree WK and Linder ME. SNAP-25 is targeted to the plasma membrane through a novel membrane-binding domain. (1999) J Biol Chem. 274, 21313-8 Pubmed J Biol Chem
Gonzalo S and Linder ME. SNAP-25 palmitoylation and plasma membrane targeting require a functional secretory pathway. (1998) Mol Biol Cell. 9, 585-97 Pubmed Mol Biol Cell PMC Article
Colombo MI, Gonzalo S, Weidman P and Stahl P. Characterization of trypsin-sensitive factor(s) required for endosome-endosome fusion. (1991) J Biol Chem. 266, 23438-45 Pubmed J Biol Chem
Gonzalo S. DNA damage and lamins. (2014) Adv Exp Med Biol. 773, 377-99 Pubmed Adv Exp Med Biol PMC Article
Gonzalo S and Kreienkamp R. Methods to Monitor DNA Repair Defects and Genomic Instability in the Context of a Disrupted Nuclear Lamina. (2016) Methods Mol Biol. 1411, 419-37 Pubmed Methods Mol Biol PMC Article
Das A, Grotsky DA, Neumann MA, Kreienkamp R, Gonzalez-Suarez I, Redwood AB, Kennedy BK, Stewart CL and Gonzalo S. Lamin A Δexon9 mutation leads to telomere and chromatin defects but not genomic instability. (2013) Nucleus. 4, 410-9 Pubmed Nucleus PMC Article
Vindigni A and Gonzalo S. The two faces of DNA repair: disease and therapy. (2013) Mo Med. 110, 314-9 Pubmed Mo Med PMC Article
Gonzalez-Suarez I and Gonzalo S. Crosstalk between chromatin structure, nuclear compartmentalization, and telomere biology. (2008) Cytogenet Genome Res. 122, 202-10 Pubmed Cytogenet Genome Res
Kreienkamp R and Gonzalo S. Hutchinson-Gilford Progeria Syndrome: Challenges at Bench and Bedside. (2019) Subcell Biochem. 91, 435-451 Pubmed Subcell Biochem
Gonzalez-Suarez I and Gonzalo S. Nurturing the genome: A-type lamins preserve genomic stability. (2010) Nucleus. 1, 129-35 Pubmed Nucleus PMC Article