Structural biology and single-molecule studies of Antiphospholipid Syndrome
Through a variety of biochemical and biophysical methods, our lab studies the dynamic personalities of proteins involved in Antiphospholipid Syndrome, such as thiol-oxidoreductases, complement and clotting factors. Our goals are to 1) visualize such proteins as they perform their physiological functions in real-time and 2) define how these functions are altered by antiphospholipid antibodies. We ultimatly employ this knowledge of protein dynamics for the design of novel compounds or biologics to better treat and diagnose APS.
“All truths are easy to understand once they are discovered; the point is to discover them” (Galileo Galilei)
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