This is WHAT we do…We study the molecular mechanisms of blood coagulation. Our main focus is on Antiphospholipid Syndrome (APS), an autoimmune disorder that causes unexpected and life-threatening blood clots. 

This is WHY we do it…Blood clots affect as many as 900,000 people each year, leading to approximately 100,000 premature deaths, only in the US. In most cases, like for APS, there is no cure. Diagnosis remains challenging and treatment suboptimal.

This is HOW we do it…Our approach is rooted in rigorous structural and mechanistic biochemistry. We study antigen-antibody interactions, investigate new targets for lowering thrombotic risk, and develop monoclonal antibodies and nanobodies as research tools and potential therapeutics.