Molecular Mechanisms of thrombosis and Hemostasis

OUR GOAL

Targeted Diagnostics and Therapeutics

OUR APPROACH

It is hard to come up with game-changing new drugs without a more in-depth knowledge of the fundamental mechanisms of disease
State-of-the-art Techniques

In our laboratory, we strive to understand the pathophysiological mechanisms that lead to many life-threatening disorders such as cancer, neurodegeneration, ‚Äčand autoimmunity. To achieve our goals, we apply a unique combination of structural biology, single molecule spectroscopy, enzymology and protein engineering

  • X-ray crystallography, SAXS, Electron Microscopy

  • sm-PIE-FRET, smTIRF-FRET, FCS

  • kinetic assays, protein-protein interactions

  • Molecular Cloning, Mutagenesis, Incorporation of Non-Natural Amino Acids

OUR TEAM

Nicola Pozzi, Ph.D.

Mathivanan Chinnaraj, Ph.D.

William Planer, MS, MSF, MBA

CONTACT US

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