Our lab’s logo incorporates three key elements of our research interests: Protein Disulfide Isomerase (PDI), an IgG antiphospholipid antibody in red, and the small molecule vitamin K in black. PDI represents our focus on the structural enzymology of thiol-isomerases. The IgG symbolizes an antiphospholipid antibody and related technologies we’re developing to improve the diagnosis and treatment of antiphospholipid syndrome. Finally, vitamin K is a crucial cofactor for proper blood coagulation.
Interestingly, the name “vitamin K” comes from the German “Koagulations-Vitamin.” Warfarin, a famous vitamin K analogue, is widely used as an anticoagulant, especially for treating APS patients. Vitamin K was discovered by Edward A. Doisy, the founder of our department. He was awarded the Nobel Prize in Medicine in 1943 for this discovery, and his legacy continues to inspire us.