The research in the lab focuses on characterization of novel DNA binding proteins in DNA replication and repair. We are investigating how these proteins act alone, in competition, or in coordination with other protein complexes

Our research combines rigorous biochemical assays with unbiased cellular CRISPR and proteomics screens to ask questions including:

• What novel DNA binding proteins are important at the replication fork?
• What additional sites of exposed DNA in the cell do these complexes localize and operate on?
• How are these DNA binding proteins regulated on their own and as part of complexes?