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Oleg Kisselev, Ph.D.
Secondary Professor of Ophthalmology
Associate Dean for Clinical Research and Administrative Chair, SLU IRB

Studies on the mechanism of transmembrane signal transduction mediated by heterotrimeric G-proteins, which are responsible for the transmission of information about extracellular messangers.

Office: Schwitalla Hall M100
Voice: (314) 977-6301

Research Interests

We are interested in the universal mechanism of transmembrane signal transduction mediated by heterotrimeric G-proteins, which are responsible for the transmission of information about extracellular messengers such as hormones, neurotransmitters and sensory stimuli, including visual signals. We use structural, biochemical and electrophysiological tools to study retinal signaling pathways. Our translational vision research program aims at the structure-based design of therapeutics acting on the receptor/G-protein interface and modulating constitutive activity of the receptors that are at the basis of various retina degenerative disorders.

Recent Publications

Department of Biochemistry and Molecular Biology
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