Dorota Skowyra, Ph.D.
Associate Professor

Studies on the role, function, and regulation of the ubiquitin-proteasome system in health and disease.

Office: DRC 405
Voice: (314) 977-9280

Research Interests

Skowyra Lab: The Ubiquitin-Proteasome System

Biological Roles:
  • human cell culture
  • fluorescent probes
  • high content screening
  • purified proteins
  • activity assays
  • structure/function
  • disease risk assessment
  • targeted protein degradation
Current Projects:
  • Dux4 proteolysis in FSHD muscular dystrophy - From mechanism to applications
  • Proteasome load tolerance as a risk controller in protein aggregation diseases

Recent Publications

Department of Biochemistry and Molecular Biology