Tinghai Xu, Ph.D.
Assistant Professor

Mechanistic understanding of DNA methylation, histone modification, and chromatin remodeling.

Office: DRC 525

Research Interests

Our research focuses on investigation of the relationship between DNA methylation, histone modifications, and chromatin remodeling using structural and cell biology methods to provide fundamental insights for therapeutic manipulation of DNA methylation in human disease and structure-based drug discovery.

Our research focuses on three important topics:
  1. DNA methyltransferase and nucleosome complexes
  2. Remodeler-mediated DNA methylation on chromatin
  3. Chromatin-associated protein complexes

Recent Publications

Department of Biochemistry and Molecular Biology